Showing posts with label sucralose. Show all posts
Showing posts with label sucralose. Show all posts

How Sugar Substitutes Confuse Your Body






By Dr. Mercola
If you've added the artificial sweetener sucralose (brand name Splenda) to your diet because you think it's a healthy alternative to sugar, you're being dangerously misled. Research from the Ramazzini Institute has linked the popular sugar alternative to cancer, specifically leukemia. 
The findings were first presented at a London cancer conference in 2012 and prompted The Center for Science in the Public Interest (CSPI) to downgrade Splenda from its "safe" category to one of "caution."
Now that the study has been published in a peer-reviewed journal, CSPI has again downgraded Splenda, this time from "caution" to "avoid."

Splenda May Increase Risk of Cancer in Mice

The researchers fed mice Splenda beginning prenatally and continuing for their entire lifespan. The mice were fed varying concentrations of the artificial sweetener: 0 ppm (parts per million), 500 ppm, 2,000 ppm, 8,000 ppm or 16,000 ppm. 
A significant increase in cancerous tumors was seen among male mice, and the risk increased along with the dose. The risk of leukemia in male mice also significantly increased, especially at Splenda doses of 2,000 to 16,000 ppm.1According to the study:
"These findings do not support previous data that sucralose is biologically inert. More studies are necessary to show the safety of sucralose, including new and more adequate carcinogenic bioassay on rats.
Considering that millions of people are likely exposed, follow-up studies are urgent."
CSPI explained that the only other long-term feeding studies conducted on Splenda were conducted by its manufacturer. The new study, they said:2
" … [I]s more powerful than the industry-funded studies, which tested fewer animals, started exposing the animals beginning at adolescence as opposed to in utero, and ended earlier in the animals' lives."
After more than a decade, CSPI has finally gotten it right about Splenda in recommending that consumers avoid it. For the record, however, CSPI is generally an organization whose guidelines need to be taken with a grain of salt.
For instance, while recommending that people avoid artificial sweeteners like sucralose, aspartame and saccharin, they still consider drinking diet soda to be safer than drinking regular soda. 

Splenda Is Found in 4,500 Products

If you'd like to heed the warnings and cut Splenda from your diet, be aware that it's found in more than 4,500 products. Splenda has been smartly marketed, and it's most known for its tag line "made from sugar so it tastes like sugar."
It's earned a reputation for being somehow safer than other artificial sweeteners like aspartame, which is why PepsiCo ditched aspartame in its Diet Pepsi in 2015 and replaced it with none other than Splenda.
Splenda became one of the top-selling artificial sweeteners in the U.S. in a very short period of time. Between 2000 and 2004, the percentage of U.S. households using Splenda products jumped from 3 percent to 20 percent. By 2012, Splenda generated sales of nearly $288 million.3
But make no mistake; Splenda is far from natural, even though it technically does start off as a sugar molecule. In the five-step patented process of making sucralose, three chlorine molecules are added to a sucrose or sugar molecule.
A sucrose molecule is a disaccharide that contains two single sugars bound together: glucose and fructose. The chemical process to make sucralose alters the chemical composition of the sugar so much that it is somehow converted to a fructose-galactose molecule.
This type of sugar molecule does not occur in nature, and therefore your body does not possess the ability to properly metabolize it. As a result of this "unique" biochemical make-up, the manufacturers claim that Splenda is not digested or metabolized by your body, making it have zero calories.
Splenda is supposed to pass right through you. However, the research (which is primarily extrapolated from animal studies) indicates that about 15 percent of sucralose is, in fact, absorbed into your digestive system and ultimately stored in your body.

Splenda May Decimate Your Gut Bacteria

If the potential cancer finding isn't enough to sway you away from this toxic artificial sweetener, be aware that Splenda may wreak havoc on your gut bacteria, which could have an untold number of consequences on your health.
An animal study published in the Journal of Toxicology and Environmental Health, for instance, found that Splenda reduces the amount of beneficial bacteria in rat intestines by 50 percent while also increasing the pH level.
It also affected a glycoprotein that may affect the way certain drugs are metabolized by the body.4 The researchers explained:
"At the end of the 12-wk treatment period, the numbers of total anaerobes, bifidobacteria, lactobacilli, Bacteroides, clostridia, and total aerobic bacteria were significantly decreased … Splenda also increased fecal pH
These changes occurred at Splenda dosages that contained sucralose at 1.1 to 11 mg/kg (the U.S. FDA Acceptable Daily Intake for sucralose is 5 mg/kg).
Evidence indicates that a 12-wk administration of Splenda exerted numerous adverse effects, including (1) reduction in beneficial fecal microflora, (2) increased fecal pH, and (3) enhanced expression levels of P-gp, CYP3A4, and CYP2D1, which are known to limit the bioavailability of orally administered drugs."

Splenda May Have Neurotoxic Effects and Is Found in Water

Research published in 2014 detailed Splenda's oxidative effects and suggested the sweetener may have neurotoxic properties. 
The researchers, who assessed the effects of sucralose on water fleas, concluded that: "exposure to sucralose may induce neurological and oxidative mechanisms with potentially important consequences for animal behavior and physiology."5
The enzyme acetylcholinesterase is found in all animals, and for researchers looking for possible effects that artificial sweeteners like Splenda might have on animals and humans, this new information was disturbing. 
If for no other reason, that’s why it’s so important to find out the consequences of Splenda exposure sooner rather than later, as the chemicals have already been detected in municipal effluents and surface waters in both the U.S. and Europe.6

Splenda Raises Your Insulin Levels

Far from being an inert substance, research also shows that Splenda affects your body's insulin response. When study participants drank a Splenda-sweetened beverage, their insulin levels rose about 20 percent higher than when they consumed only water prior to taking a glucose-challenge test.7
Blood sugar levels also peaked at a higher level, "So the artificial sweetener was related to an enhanced blood insulin and glucose response," researchers noted, adding:8
"Although we found that sucralose affects the glucose and insulin response to glucose ingestion, we don't know the mechanism responsible. We have shown that sucralose is having an effect. In obese people without diabetes, we have shown sucralose is more than just something sweet that you put into your mouth with no other consequences.
What these all mean for daily life scenarios is still unknown, but our findings are stressing the need for more studies. Whether these acute effects of sucralose will influence how our bodies handle sugar in the long term is something we need to know."






Artificial Sweeteners Confuse Your Metabolism 

When you eat something sweet, your brain releases dopamine, which activates your brain's reward center. The appetite-regulating hormone leptin is also released, which eventually informs your brain that you are "full" once a certain amount of calories have been ingested. 
However, when you consume something that tastes sweet but doesn't contain any calories, like an artificial sweetener, your brain's pleasure pathway still gets activated by the sweet taste. However, there's nothing to deactivate it since the calories never arrive. 
Artificial sweeteners basically trick your body into thinking that it's going to receive sugar (calories), but when the sugar doesn't come your body continues to signal that it needs more, which results in carb cravings. 
Contrary to industry claims, research over the last 30 years — including several large-scale prospective cohort studies — has shown that artificial sweeteners stimulate appetite, increase cravings for carbs, and produce a variety of metabolic dysfunctions that promote fat storage and weight gain — often to the researchers' great surprise.
For instance, a 2010 review published in the Yale Journal of Biology and Medicine revealed the correlation between increased usage of artificial sweeteners in food and drinks and the corresponding rise in obesity. More than 11,650 children aged 9 to 14 were included in this study. Each daily serving of diet beverage was associated with a body mass index (BMI) increase of 0.16 kg/m2.
You can see the trends for yourself in the Yale Journal of Biology and Medicine graphic below, which clearly refutes the beverage industry's claims that artificially sweetened diet soda aids weight loss. 

Are There Safer Artificial Sweeteners?

I recommend avoiding artificial sweeteners of any kind, as each is linked with its own risks. Aspartame is perhaps the most dangerous of the bunch. At least it's one of the most widely used and has the most reports of adverse effects. There are also hundreds of scientific studies demonstrating its harmful effects.
Sugar alcohols are another option on the market. They can be identified by the commonality of "ol" at the end of their name, such as xylitol glucitol, sorbitol, maltitol, mannitol, glycerol, and lactitol. They're not as sweet as sugar, and they do contain fewer calories, but they're not calorie-free. So don't get confused by the "sugar-free" label on foods containing these sweeteners. 
One reason that sugar alcohols provide fewer calories than sugar is because they're not completely absorbed into your body. Because of this, eating too many foods containing sugar alcohols can lead to abdominal gas and diarrhea. It's also worth noting that maltitol, a commonly used sugar alcohol, spikes blood sugar almost as much as a starchy new potato.
Xylitol, in comparison, does not have a great effect on your blood sugar, so from that perspective it may be a better choice. In moderation, some sugar alcohols can be a better choice than artificial sweeteners like Splenda and aspartame. Of the various sugar alcohols, xylitol is one of the best. When it is pure, the potential side effects are minimal, and it actually comes with some benefits such as fighting tooth decay.
All in all, I would say that xylitol is reasonably safe, and potentially even a mildly beneficial sweetener. As a side note, xylitol is toxic to dogs and some other animals, so be sure to keep it out of reach of your family pets.)
That being said, two of the best natural sugar substitutes are from the plant kingdom: Stevia and Luo Han Guo (also spelled Luo Han Kuo). Stevia, a highly sweet herb derived from the leaf of the South American stevia plant, is sold as a supplement. It's completely safe in its natural form and can be used to sweeten most dishes and drinks.
Luo Han Kuo is similar to Stevia, but it's a bit more expensive and harder to find. In China, the Luo Han fruit has been used as a sweetener for centuries, and it's about 200 times sweeter than sugar.

How to Break Free From Artificial Sweeteners

The best option of all is to break free from the grip of artificial sweeteners, which starts by eliminating your sugar cravings. If you aren't craving something sweet, you probably won't have a desire to reach for an artificial sweetener.
First, I highly recommend trying an energy psychology technique called Turbo Tapping, which has helped many "soda addicts" kick their habit, and it should work for any type of sweet craving (or diet soda craving) you may have. A few other tricks to try to kick your sugar cravings:
  • Exercise: Anyone who exercises intensely on a regular basis will know that significant amounts of cardiovascular exercise is one of the best "cures" for food cravings. It always amazes me how my appetite, especially for sweets, dramatically decreases after a good workout. 
  • I believe the mechanism is related to the dramatic reduction in insulin levels that occurs after exercise. Additionally, if you do eat sugars or fruits around the time of the exercise, your sugar levels will not rise as it will metabolized for fuel
  • Organic, black coffee: Coffee is a potent opioid receptor antagonist, and contains compounds such as cafestrol — found plentifully in both caffeinated and decaffeinated coffee — which can bind to your opioid receptors, occupy them and essentially block your addiction to other opioid-releasing food.9,10 This may profoundly reduce the addictive power of other substances, such as sugar.
  • Sour taste, such as that from cultured vegetables, helps to reduce sweet cravings, too. This is doubly beneficial, as fermented vegetables also promote gut health. You can also try adding lemon or lime juice to your water.




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The 5 Worst Sweeteners And Their Organic Replacements




We all have a sweet tooth every once in a while and it’s okay to have that. In fact, it’s a natural part of our biology. In Ayurveda, an form of medicine originating in India it is taught that there are 6 different tastes to experience to create harmony within the body. These tastes are astringent, bitter, pungent, sour, salty and last but not least… sweet!
Sweet food tastes great and often helps our brain chemistry making is feel happier. Sweet food has it’s use and value in our life and health if understood and used for our health benefit as opposed to against it. There are sweeteners though that are made form GM organisms, and other toxic by-products that cause disruption within the body.  Today I decided to compile a list of the top 5 worst sweeteners, the most harmful sweeteners and to give you their organic equivalent that actually has nutritional value.
Most sweeteners are full of chemicals, toxins, preservatives and even endocrine disruptors negatively affecting your hormones and health as a whole.
Here’s a list of the top 5 worst sweeteners and their replacements:
1. White Sugar: Often made from sugar cane but can also be created from genetically modified beets. White sugar is one of the worst things to ingest for your body overall across the board so it’s best to avoid. A great replacement is brown organic turbinado sugar.
2. Aspartame (Found in Nutrasweet/Equal): Aspartame does not metabolize well in the body at all. The body digests small doses of aspartame in a way that harms the liver. The profile of Aspartame (the chemcial composition) does not mimic nature at all in any way and is one of the worst sweeteners you can choose. Worse than white sugar even. A great replacement is organic coconut sugar which is packed full of vitamins, electrolytes and minerals.
3. Sucralose (splenda): Another synthetic chemical based toxic sweetener made of chemicals and junk. It’s a synthetic covalently bound chloride compound. Agent Orange and PCB are both other examples of synthetic covalently bound chloride compounds. This is toxic and once again worse than white sugar. I love organic stevia as a replacement for this because it is super sweet and doesn’t negatively impact your blood sugar levels in any way and in fact helps to balance them. This specific stevia has so many different incredibly delicious flavors as well which really make it that much tastier.
4. High Fructose Corn Syrup: The journal cancer research published in 2010 that high fructose corn syrup was found to feed cancer. This is not surprising, especially since white sugar has also been known to feed cancer as well. HFCS is also genetically modified which means it has plenty of laced chemicals from Monsanto in it as well. I like raw unpasteurized organic honey as a replacement. It’s full of enzymes and has so much value for your health, specifically your liver and immune system.
5. Agave: I’ve never been a big fan of agave but the more I learn about it the more I avoid it. Which is unfortunate because some health food companies use this as a sweetener. The main problem I see with it is that the fructose (fruit sugar content) in agave is higher than ANY other commercial sweetener, causing liver and metabolism issues if consumed regularly. I like organic sunroot jerusalam arthichoke sweetener as a replacement for this. This sweetener is full of nutrition as well and is a great prebiotic sweetener that enhances your intestinal health. It also tastes a lot like molasses in it’s own unique way which I love! I highly recommend trying it at least once in your life!
You can still get that sweet tooth craving without spiking your blood sugar levels, weakening your immune system and liver and causing overall havoc within your body. It’s just about choosing a healthier sweetener for you. If you’re looking to balance blood glucose levels then go with stevia. If you’re looking for prebiotics for intestinal health go with the sunroot arthichoke sweetener. If you want immunity and liver health go with raw honey. Each sweetener has it’s own list of health benefits and can add value, energy and value to your life instead of take away from it.
I hope this list of sweeteners to avoid and ones to replace them with is helpful to you and your health! Enjoy the rest of your day.



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